Therapeutic effect of three-dimensional hanging drop cultured human umbilical cord mesenchymal stem cells on osteoarthritis in rabbits

Abstract Background Mesenchymal stem cells (MSCs) have shown a positive effect on Osteoarthritis (OA), but the efficacy is still not significant in clinical. Conventional two-dimensional (2D) monolayer culture method is prone to cause MSCs undergoing replication senescence, which may affect the func...

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التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Stem Cell Research & Therapy
المؤلفون الرئيسيون:	Qiang Fu, Mei Han, Xiaoyu Dai, Ruian Lu, Enjie Deng, Xuemei Shen, Feng Ou, Yongguang Pu, Xueqin Xie, Kang Liu, Yuanshan Gan, Dong Li
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	BMC 2024-09-01
الموضوعات:	Mesenchymal stem cells 3D hanging drop method Osteoarthritis Cartilage regeneration Immunomodulatory
الوصول للمادة أونلاين:	https://doi.org/10.1186/s13287-024-03905-y