Endogenous Interleukin-17a Contributes to Normal Spatial Memory Retention but Does Not Affect Early Behavioral or Neuropathological Outcomes after Experimental Traumatic Brain Injury

Interleukin-17 (IL-17) is a proinflammatory cytokine primarily secreted in the brain by inflammatory T lymphocytes and glial cells. IL-17+ T-helper (Th17) cells are increased in the ipsilateral hemisphere after experimental traumatic brain injury (TBI), and IL-17 levels are increased in serum and br...

Full description

Bibliographic Details

Published in:	Neurotrauma Reports
Main Authors:	Dennis W. Simon, Itay Raphael, Kendall M. Johnson, C. Edward Dixon, Vincent Vagni, Keri Janesko-Feldman, Patrick M. Kochanek, H?lya Bayir, Robert S.B. Clark, Mandy J. McGeachy
Format:	Article
Language:	English
Published:	Mary Ann Liebert 2022-09-01
Subjects:	head trauma interleukin lymphocyte neuroinflammation
Online Access:	https://www.liebertpub.com/doi/full/10.1089/NEUR.2022.0017