Extracellular vesicles from human‐induced pluripotent stem cell‐derived neural stem cells alleviate proinflammatory cascades within disease‐associated microglia in Alzheimer's disease

Abstract As current treatments for Alzheimer's disease (AD) lack disease‐modifying interventions, novel therapies capable of restraining AD progression and maintaining better brain function have great significance. Anti‐inflammatory extracellular vesicles (EVs) derived from human induced plurip...

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Bibliographic Details

Published in:	Journal of Extracellular Vesicles
Main Authors:	Leelavathi N. Madhu, Maheedhar Kodali, Raghavendra Upadhya, Shama Rao, Yogish Somayaji, Sahithi Attaluri, Bing Shuai, Maha Kirmani, Shreyan Gupta, Nathaniel Maness, Xiaolan Rao, James J. Cai, Ashok K. Shetty
Format:	Article
Language:	English
Published:	Wiley 2024-11-01
Subjects:	Anti‐inflammatory effects disease‐associated microglia extracellular vesicles human induced pluripotent stem cell‐derived neural stem cells inflammasomes interferon 1 signalling
Online Access:	https://doi.org/10.1002/jev2.12519