The role of genetic polymorphisms on drug response in Alzheimer’s disease: a systematic review

Abstract Alzheimer’s disease (AD) is the most common neurodegenerative disorder, affecting over 32 million people globally. The variability in treatment response to AD medications is influenced by genetic factors, sex, comorbidities, and medication history. Pharmacogenomics, the study of how an indi...

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Bibliographic Details

Published in:	BMC Medical Genomics
Main Authors:	Fresthel Monica M. Climacosa, Eric David B. Ornos, Nicole Clarence Louise L. Gapaz, Mary Gale R. Guantia, Joana Marie C. Cruz, Rafael Vincent M. Manalo, Melody L. Yu, Almeera P. Qureshi, Ajina C. Carampel, Joannes Luke B. Asis, John Carlo B. Reyes, Aira B. Dacasin, Veeda Michelle M. Anlacan
Format:	Article
Language:	English
Published:	BMC 2025-10-01
Subjects:	Pharmacogenomics Alzheimer’s disease Drug response Genetic polymorphisms
Online Access:	https://doi.org/10.1186/s12920-025-02225-1