Role of autophagy in cancer-associated fibroblast activation, signaling and metabolic reprograming

Tumors not only consist of cancerous cells, but they also harbor several normal-like cell types and non-cellular components. cancer-associated fibroblasts (CAFs) are one of these cellular components that are found predominantly in the tumor stroma. Autophagy is an intracellular degradation and quali...

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Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Dyana Sari, Devrim Gozuacik, Yunus Akkoc
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-01-01
Subjects:	cancer-associated fibroblasts (CAFs) autophagy tumor microenvironment (TME) fibroblast transdifferentiation cancer
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2023.1274682/full