Modulation of riboflavin biosynthesis and utilization in mycobacteria

ABSTRACT Riboflavin (vitamin B2) is the precursor of the flavin coenzymes, FAD and FMN, which play a central role in cellular redox metabolism. While humans must obtain riboflavin from dietary sources, certain microbes, including Mycobacterium tuberculosis (Mtb), can biosynthesize riboflavin de novo...

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Bibliographic Details
Published in:Microbiology Spectrum
Main Authors: Melissa D. Chengalroyen, Carolina Mehaffy, Megan Lucas, Niel Bauer, Mabule L. Raphela, Nurudeen Oketade, Digby F. Warner, Deborah A. Lewinsohn, David M. Lewinsohn, Karen M. Dobos, Valerie Mizrahi
Format: Article
Language:English
Published: American Society for Microbiology 2024-08-01
Subjects:
tuberculosis
Mycobacterium
FAD
FMN
drug discovery
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03207-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.03207-23

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