Cancer-associated fibroblasts: The chief architect in the tumor microenvironment

Stromal heterogeneity of tumor microenvironment (TME) plays a crucial role in malignancy and therapeutic resistance. Cancer-associated fibroblasts (CAFs) are one of the major players in tumor stroma. The heterogeneous sources of origin and subsequent impacts of crosstalk with breast cancer cells fla...

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Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Mrinmoy Sarkar, Tristan Nguyen, Esheksha Gundre, Olajumoke Ogunlusi, Mohanad El-Sobky, Biplab Giri, Tapasree Roy Sarkar
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-01-01
Subjects:	CAF breast cancer tumor microenvironment heterogeneity targeting
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2023.1089068/full