Roasted <i>Astragalus membranaceus</i> Inhibits Cognitive Decline in 5xFAD Mice by Activating the BDNF/CREB Pathway

Alzheimer’s disease (AD) is a complex pathological process that incurs significant societal costs, yet effective treatments have not yet been developed. Novel compounds targeting β-amyloid, based on the amyloid cascade hypothesis, have failed to demonstrate clinical efficacy. Among natural products...

Full description

Bibliographic Details

Published in:	Antioxidants
Main Authors:	Ji Hye Yoon, Jinyoung Maeng, Yujin Kim, Gidong Koo, Jeong Seok Shim, Sangeun Im, Subin Jung, Jihwan Shin, Sung-Su Kim, Sungho Maeng
Format:	Article
Language:	English
Published:	MDPI AG 2025-10-01
Subjects:	dementia Alzheimer’s disease <i>Astragalus membranaceus</i> roasted <i>Astragali radix</i> 5xFAD
Online Access:	https://www.mdpi.com/2076-3921/14/10/1250