The Cadherin Cry1Ac Binding-Region is Necessary for the Cooperative Effect with ABCC2 Transporter Enhancing Insecticidal Activity of <i>Bacillus thuringiensis</i> Cry1Ac Toxin

<i>Bacillus thuringiensis</i> Cry1Ac toxin binds to midgut proteins, as cadherin (CAD) and ABCC2 transporter, to form pores leading to larval death. In cell lines, co-expression of CAD and ABCC2 enhance Cry1Ac toxicity significantly, but the mechanism remains elusive. Here, we show that...

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Bibliographic Details

Published in:	Toxins
Main Authors:	Yuemin Ma, Jianfeng Zhang, Yutao Xiao, Yanchao Yang, Chenxi Liu, Rong Peng, Yongbo Yang, Alejandra Bravo, Mario Soberón, Kaiyu Liu
Format:	Article
Language:	English
Published:	MDPI AG 2019-09-01
Subjects:	<i>Helicoverpa armigera</i> <i>Spodoptera litura</i> cadherin ABCC2 transporter <i>Bacillus thuringiensis</i> synergism Cry1Ac
Online Access:	https://www.mdpi.com/2072-6651/11/9/538