How does Nogo receptor influence demyelination and remyelination in the context of multiple sclerosis?

Multiple sclerosis (MS) can progress with neurodegeneration as a consequence of chronic inflammatory mechanisms that drive neural cell loss and/or neuroaxonal dystrophy in the central nervous system. Immune-mediated mechanisms can accumulate myelin debris in the disease extracellular milieu during c...

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Bibliographic Details

Published in:	Frontiers in Cellular Neuroscience
Main Authors:	Zahra Rashidbenam, Ezgi Ozturk, Maurice Pagnin, Paschalis Theotokis, Nikolaos Grigoriadis, Steven Petratos
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-06-01
Subjects:	myelin debris Nogo-A Nogo receptor 1 Nogo receptor 1-dependent axonopathy oligodendrocyte progressive multiple sclerosis
Online Access:	https://www.frontiersin.org/articles/10.3389/fncel.2023.1197492/full