Spontaneous and optogenetically induced cortical spreading depolarization in familial hemiplegic migraine type 1 mutant mice

Mechanisms underlying the migraine aura are incompletely understood, which to large extent is related to a lack of models in which cortical spreading depolarization (CSD), the correlate of the aura, occurs spontaneously. Here, we investigated electrophysiological and behavioural CSD features in free...

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Bibliographic Details

Published in:	Neurobiology of Disease
Main Authors:	Inge C.M. Loonen, Rob A. Voskuyl, Maarten Schenke, Sandra H. van Heiningen, Arn M.J.M. van den Maagdenberg, Else A. Tolner
Format:	Article
Language:	English
Published:	Elsevier 2024-03-01
Subjects:	Behaviour Cortical excitability Cortical spreading depolarization Mouse model Optogenetics
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996124000044