SENP1 drives glycolysis and cisplatin resistance in gastric cancer via desumoylating ENO1

Abstract Background Gastric cancer remains a leading cause of cancer-related mortality in world, with advanced-stage patients facing poor prognosis despite emerging therapies. SUMOylation modification is a major post-translation modification, which is essential for cellular behaviors. However, the p...

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الحاوية / القاعدة:	Journal of Experimental & Clinical Cancer Research
المؤلفون الرئيسيون:	Yuan Fang, Yunru Gu, Tingting Xu, Peng Wang, Xi Wu, Haoyang Shen, Yangyue Xu, Zixiang Xu, Lei Cao, Xiao Li, Hao Wu, Yongqian Shu, Pei Ma
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	BMC 2025-10-01
الموضوعات:	Gastric cancer SUMOylation SENP1 Glycolysis Cisplatin
الوصول للمادة أونلاين:	https://doi.org/10.1186/s13046-025-03543-z