Unraveling the causal links and novel molecular classification of Crohn’s disease in breast Cancer: a two-sample mendelian randomization and transcriptome analysis with prognostic modeling

Abstract Background Crohn’s disease (CD), a prominent manifestation of chronic gastrointestinal inflammation, and breast cancer (BC), seemingly disparate in the medical domain, exhibit a shared characteristic. This convergence arises from their involvement in chronic inflammation and immune response...

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Bibliographic Details

Published in:	BMC Cancer
Main Authors:	Xin Yu, Yushuai Yu, Xiewei Huang, Zirong Jiang, Qing Wang, Xiaoqin Yu, Chuangui Song
Format:	Article
Language:	English
Published:	BMC 2024-09-01
Subjects:	Crohn’s Disease Breast Cancer Mendelian randomization Prognostic model Molecular classification
Online Access:	https://doi.org/10.1186/s12885-024-12838-x