Eine einfache Synthese von 2-Oxazolin-5-onen und verwandten Verbindungen via Amidcyclisierungen
Acid catalyzed cyclization of diamides 3 leads to 2-oxazolin-5-ones of type 2 in high yield (Scheme 2). Resolution of racemic oxazolinone 2b is accomplished by reaction with (S)-phenylalanin dimethylamide ((S)-5) to yield a diastereomeric mixture of triamides 6 (Scheme 3) and cleavage of the diaste...
| Published in: | CHIMIA |
|---|---|
| Main Authors: | , |
| Format: | Article |
| Language: | German |
| Published: |
Swiss Chemical Society
1982-02-01
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| Online Access: | https://www.chimia.ch/chimia/article/view/9550 |