Motion based ex vivo (MOTEX) culture of breast tumor slices sustains microenvironment composition

Personalized medicine for breast cancer (BrC) requires predictive biomarkers to select the optimal therapeutic option for each individual patient. Personalization of chemotherapy or immunotherapy responses is particularly challenging, as molecular markers do not appear to be sufficiently predictive...

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Bibliographic Details

Published in:	Neoplasia: An International Journal for Oncology Research
Main Authors:	Zofia M. Komar, Mieke Bavelaar, Ellen Kageler, Nicole S. Verkaik, Mandy M. van Rosmalen, Carolien H.M. van Deurzen, Michael A. den Bakker, Roland Kanaar, Adriaan B Houtsmuller, Thierry P.P. van den Bosch, Agnes Jager, Dik C. van Gent
Format:	Article
Language:	English
Published:	Elsevier 2025-10-01
Subjects:	Tumor microenvironment Breast cancer Treatment prediction Tumor infiltrating lymphocytes (TILs)
Online Access:	http://www.sciencedirect.com/science/article/pii/S1476558625001009