Inhibition of Stat3‐mediated astrogliosis ameliorates pathology in an Alzheimer's disease model

Abstract Reactive astrogliosis is a hallmark of Alzheimer's disease (AD), but its role for disease initiation and progression has remained incompletely understood. We here show that the transcription factor Stat3 (signal transducer and activator of transcription 3), a canonical inducer of astro...

Full description

Bibliographic Details

Published in:	EMBO Molecular Medicine
Main Authors:	Nicole Reichenbach, Andrea Delekate, Monika Plescher, Franziska Schmitt, Sybille Krauss, Nelli Blank, Annett Halle, Gabor C Petzold
Format:	Article
Language:	English
Published:	Springer Nature 2019-01-01
Subjects:	Alzheimer's disease astrocytes astrogliosis glia Stat3
Online Access:	https://doi.org/10.15252/emmm.201809665