The Time-Course of Antioxidant Irisin Activity: Role of the Nrf2/HO-1/HMGB1 Axis

The production of free radicals is one of the basic mechanisms giving rise to the antimicrobial activity of macrophages; however, excessive accumulation of reactive oxygen species (ROS) can lead to cell damage, cell death, and release of the highly proinflammatory alarmin high-mobility group box 1 (...

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Bibliographic Details
Published in:Antioxidants
Main Authors: Agnieszka Irena Mazur-Bialy, Ewa Pocheć
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Subjects:
Online Access:https://www.mdpi.com/2076-3921/10/1/88