The Slingshot phosphatase 2 is required for acrosome biogenesis during spermatogenesis in mice

The acrosome is a membranous organelle positioned in the anterior portion of the sperm head and is essential for male fertility. Acrosome biogenesis requires the dynamic cytoskeletal shuttling of vesicles toward nascent acrosome which is regulated by a series of accessory proteins. However, much rem...

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Bibliographic Details

Published in:	eLife
Main Authors:	Ke Xu, Xianwei Su, Kailun Fang, Yue Lv, Tao Huang, Mengjing Li, Ziqi Wang, Yingying Yin, Tahir Muhammad, Shangming Liu, Xiangfeng Chen, Jing Jiang, Jinsong Li, Wai-Yee Chan, Jinlong Ma, Gang Lu, Zi-Jiang Chen, Hongbin Liu
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2023-03-01
Subjects:	spermatogenesis Ssh2 actin remodeling acrosome biogenesis
Online Access:	https://elifesciences.org/articles/83129