Longitudinal single cell atlas identifies complex temporal relationship between type I interferon response and COVID-19 severity

Abstract Due to the paucity of longitudinal molecular studies of COVID-19, particularly those covering the early stages of infection (Days 1-8 symptom onset), our understanding of host response over the disease course is limited. We perform longitudinal single cell RNA-seq on 286 blood samples from...

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التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Nature Communications
المؤلفون الرئيسيون:	Quy Xiao Xuan Lin, Deepa Rajagopalan, Akshamal M. Gamage, Le Min Tan, Prasanna Nori Venkatesh, Wharton O. Y. Chan, Dilip Kumar, Ragini Agrawal, Yao Chen, Siew-Wai Fong, Amit Singh, Louisa J. Sun, Seow-Yen Tan, Louis Yi Ann Chai, Jyoti Somani, Bernett Lee, Laurent Renia, Lisa F P Ng, Kollengode Ramanathan, Lin-Fa Wang, Barnaby Young, David Lye, Amit Singhal, Shyam Prabhakar
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Nature Portfolio 2024-01-01
الوصول للمادة أونلاين:	https://doi.org/10.1038/s41467-023-44524-0