MAPK phosphatase 1 inhibition of p38α within lung myofibroblasts is essential for spontaneous fibrosis resolution

Fibrosis following tissue injury is distinguished from normal repair by the accumulation of pathogenic and apoptosis-resistant myofibroblasts (MFs), which arise primarily by differentiation from resident fibroblasts. Endogenous molecular brakes that promote MF dedifferentiation and clearance during...

詳細記述

書誌詳細

出版年:	The Journal of Clinical Investigation
主要な著者:	Sean M. Fortier, Natalie M. Walker, Loka R. Penke, Jared D. Baas, Qinxue Shen, Jennifer M. Speth, Steven K. Huang, Rachel L. Zemans, Anton M. Bennett, Marc Peters-Golden
フォーマット:	論文
言語:	英語
出版事項:	American Society for Clinical Investigation 2024-05-01
主題:	Cell biology Pulmonology
オンライン･アクセス:	https://doi.org/10.1172/JCI172826