Primary role of type I interferons for the induction of functionally optimal antigen-specific CD8+ T cells in HIV infectionResearch in context

Summary: Background: CD8+ T cells equipped with a full arsenal of antiviral effector functions are critical for effective immune control of HIV-1. It has nonetheless remained unclear how best to elicit such potent cellular immune responses in the context of immunotherapy or vaccination. HIV-2 has b...

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發表在:	EBioMedicine
Main Authors:	Mariela P. Cabral-Piccin, Laura Papagno, Xavier Lahaye, Federico Perdomo-Celis, Stevenn Volant, Eoghann White, Valérie Monceaux, Sian Llewellyn-Lacey, Rémi Fromentin, David A. Price, Nicolas Chomont, Nicolas Manel, Asier Saez-Cirion, Victor Appay
格式:	Article
語言:	英语
出版:	Elsevier 2023-05-01
主題:	CD8+ T cells HIV-1 HIV-2 STING Type I IFN
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2352396423001226