Combination Therapy of Allopurinol and Dantrolene and Its Role In The Prevention of Experimental Ischemia Reperfusion Injury Of The Small Intestine

Background The effect of different drugs on ischemia and reperfusion (I/R; induced oxygen free radical damage) was examined in small bowel tissue because the intestine is extremely sensitive to this pathology. Different drugs (allopurinol and dantrolene) can remove oxygen free radicals or inhibit th...

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Bibliographic Details

Published in:	Journal of Investigative Surgery
Main Authors:	Beatriz Prieto-Moure, Dolores Cejalvo-Lapeña, Mariola Belda-Antolí, Carolina Padrón-Sanz, José Miguel Lloris-Cejalvo, José Miguel Lloris-Carsí
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2021-08-01
Subjects:	intestinal ischemia/reperfusion allopurinol dantrolene antioxidant enzyme activity oxygen free radicals
Online Access:	http://dx.doi.org/10.1080/08941939.2019.1696904