Handling uncertainty in dynamic models: the pentose phosphate pathway in Trypanosoma brucei.

Dynamic models of metabolism can be useful in identifying potential drug targets, especially in unicellular organisms. A model of glycolysis in the causative agent of human African trypanosomiasis, Trypanosoma brucei, has already shown the utility of this approach. Here we add the pentose phosphate...

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Bibliographic Details

Published in:	PLoS Computational Biology
Main Authors:	Eduard J Kerkhoven, Fiona Achcar, Vincent P Alibu, Richard J Burchmore, Ian H Gilbert, Maciej Trybiło, Nicole N Driessen, David Gilbert, Rainer Breitling, Barbara M Bakker, Michael P Barrett
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-01-01
Online Access:	https://doi.org/10.1371/journal.pcbi.1003371