A rapid inducible RNA decay system reveals fast mRNA decay in P-bodies

Abstract RNA decay is vital for regulating mRNA abundance and gene expression. Existing technologies lack the spatiotemporal precision or transcript specificity to capture the stochastic and transient decay process. We devise a general strategy to inducibly recruit protein factors to modulate target...

Full description

Bibliographic Details
Published in:Nature Communications
Main Authors: Lauren A. Blake, Leslie Watkins, Yang Liu, Takanari Inoue, Bin Wu
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Online Access:https://doi.org/10.1038/s41467-024-46943-z