| 要約: | The evaluation of macroalgae as a new raw material for diverse bioprocesses is of great interest due to their fast growth rate and low environmental impact. Lactic acid has a high value in the bio-based industry and is mainly produced via fermentation. The anaerobic lactic acid fermentation of <i>Kappaphycus alvarezii</i> hydrolysates using the high-producing strain <i>Lactobacillus pentosus</i> was evaluated for detoxified and non-treated hydrolysates prepared from concentrated algal biomass and dilute acid solution mixtures. A novel hydrolysate detoxification procedure, combining activated charcoal and over-liming, for 5-hydroxymethylfurfural (HMF) removal was used. <i>L. pentosus</i> was found to successfully ferment detoxified and untreated hydrolysates produced in up to 30% and 20% <i>w</i>/<i>v</i> solutions, respectively. Significant production rates (1.88 g/L.h) and short lag phases were achieved in bioreactor fermentation operating at 37 °C and pH 6 with 150 rpm impeller velocity. A 0.94 g/g yield from fermentable sugars (galactose and glucose) was achieved, indicating that <i>K. alvarezii</i> could be used as a raw material for lactic acid production, within the context of Third Generation (3G) biorefinery.
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