Leukemic cell xenograft in zebrafish embryo for investigating drug efficacy

Zebrafish were proposed as an alternative to mammalian models to assess the efficacy and toxicity of antileukemic drugs. Due to the limited number of transgenic zebrafish leukemia models, we explored human leukemic cell xenograft in zebrafish embryos. Human leukemic cell lines and blast cells sorted...

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Bibliographic Details
Published in:Haematologica
Main Authors: Benoist Pruvot, Arnaud Jacquel, Nathalie Droin, Patrick Auberger, Didier Bouscary, Jérome Tamburini, Marc Muller, Michaela Fontenay, Johanna Chluba, Eric Solary
Format: Article
Language:English
Published: Ferrata Storti Foundation 2011-04-01
Online Access:https://haematologica.org/article/view/5942