A high cholesterol diet accelerates Alzheimer's progression by promoting fibrotic damage in rats

The literature documents the ability of oxysterols and TGFβ to cause fibrotic damage in the brain. Our study explores the potential mechanisms of oxysterol interactions with fibrotic mediators in Alzheimer's disease. It focuses on peripherally formed oxysterols and their effects on TGFβ hyperac...

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Bibliographic Details

Published in:	Brain Disorders
Main Authors:	Ashmita Das, Durlav Chowdhury, Dilip Sharma, Rahul Manna, Surendra H. Bodakhe
Format:	Article
Language:	English
Published:	Elsevier 2025-03-01
Subjects:	Alzheimer's disease High cholesterol diet TGFβ Oxysterols Rodents
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666459325000265