Investigation of fingolimod-induced lymphocyte sequestration on inflammatory response and neurological damages after cardiac arrest

Abstract Background A sepsis-like syndrome is known to occur after cardiac arrest, leading to cerebral infiltration by white blood cells (WBC). We hypothesized that pharmacological sequestration of WBC, and more specifically lymphocytes within lymphoid tissues, could reduce the cerebral infiltration...

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Bibliographic Details

Published in:	Intensive Care Medicine Experimental
Main Authors:	Yara Abi Zeid Daou, Fanny Lidouren, Antoine Bois, Naoto Watanabe, Ali Jendoubi, Estelle Faucher, Mathieu Surenaud, Sophie Chateau-Joubert, Sophie Hue, Bijan Ghaleh, Matthias Kohlhauer, Renaud Tissier
Format:	Article
Language:	English
Published:	SpringerOpen 2024-07-01
Subjects:	Cardiac arrest Resuscitation Lymphocyte Sepsis-like Inflammation Neurological dysfunction
Online Access:	https://doi.org/10.1186/s40635-024-00645-4