Autonomous artificial intelligence prescribing a drug to prevent severe acute graft-versus-host disease in HLA-haploidentical transplants

Abstract Autonomous artificial intelligence (AI) models for deciding treatment strategies are available but rarely applied prospectively in clinical settings. Here we present a prospective study of deploying daGOAT, an algorithm we have developed, as a conditional autonomous AI agent to prescribe a...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Junren Chen, Yigeng Cao, Yahui Feng, Saibing Qi, Donglin Yang, Yu Hu, Aiming Pang, Qiujin Shen, Jieya Luo, Xiaowen Gong, Rongli Zhang, Xiaolin Zhai, Xueqian Li, Wen Yan, Xianjing Zhang, Mengyun Chen, Mingming Niu, Jialin Wei, Chen Liang, Weihua Zhai, Ningning Zhao, Xueou Liu, Sichang Liu, Wangsong Zhai, Ruixin Li, Xianfeng Shao, Dong Zhang, Mingyang Wang, Pan Pan, Mingyue Xu, Wei Zhang, Yunqiang Xu, Xiaofan Zhu, Ye Guo, Hong Wang, Zhen Song, Robert Peter Gale, Mingzhe Han, Sizhou Feng, Erlie Jiang
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-09-01
Online Access:	https://doi.org/10.1038/s41467-025-62926-0