Case Report: Hydroxychloroquine in an infant with NKX2-1-associated interstitial lung disease

This study presents a case of brain–lung–thyroid syndrome caused by a pathogenic variant in the NKX2-1 gene, which is characterized by interstitial lung disease. A 7-month-old female infant was hospitalized for over half a month for cyanosis. The full-term infant developed respiratory distress syndr...

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Bibliographic Details

Published in:	Frontiers in Pediatrics
Main Authors:	Di Qing, Xuehua Xu, Tingting Shi, Huifeng Fan, Dongwei Zhang, Diyuan Yang, Gen Lu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-10-01
Subjects:	interstitial lung disease NKX2-1 gene brain–lung–thyroid syndrome hydroxychloroquine infant
Online Access:	https://www.frontiersin.org/articles/10.3389/fped.2025.1619722/full