Neuroprotective potency of mangiferin against 3-nitropropionic acid induced Huntington’s disease-like symptoms in rats: possible antioxidant and anti-inflammatory mechanisms

Huntington’s disease (HD), a neurodegenerative disease, normally starts in the prime of adult life, followed by a gradual occurrence of psychiatric disturbances, cognitive and motor dysfunction. The daily performances and life quality of HD patients have been severely interfered by these clinical si...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Pei Teng Lum, Mahendran Sekar, Lay Jing Seow, Mohd Farooq Shaikh, Alina Arulsamy, Thaarvena Retinasamy, Siew Hua Gan, Charles Gnanaraj, Norhaizan Mohd Esa, Gobinath Ramachawolran, Vetriselvan Subramaniyan, Suresh V. Chinni, Yuan Seng Wu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-07-01
Subjects:	3-nitropropionic acid Huntington’s disease mangiferin natural product neuroprotective
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1189957/full