Primary HSV-2 Infection in an Immunocompromised Patient Reveals High Diversity of Drug-Resistance Mutations in the Viral DNA Polymerase

Herpes simplex virus 2 (HSV-2) remains a significant cause of morbidity and mortality in immunocompromised individuals, despite the availability of effective antivirals. Infections caused by drug-resistant isolates are an emerging concern among these patients. Understanding evolutionary aspects of H...

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Bibliographic Details

Published in:	Viruses
Main Authors:	Hanna Helena Schalkwijk, Sarah Gillemot, Emilie Frobert, Florence Morfin, Sophie Ducastelle, Anne Conrad, Pierre Fiten, Ghislain Opdenakker, Robert Snoeck, Graciela Andrei
Format:	Article
Language:	English
Published:	MDPI AG 2025-07-01
Subjects:	herpes simplex virus 2 drug resistance viral heterogeneity viral fitness
Online Access:	https://www.mdpi.com/1999-4915/17/7/962