Secretion of genome-free hepatitis B virus--single strand blocking model for virion morphogenesis of para-retrovirus.

As a para-retrovirus, hepatitis B virus (HBV) is an enveloped virus with a double-stranded (DS) DNA genome that is replicated by reverse transcription of an RNA intermediate, the pregenomic RNA or pgRNA. HBV assembly begins with the formation of an "immature" nucleocapsid (NC) incorporatin...

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Bibliographic Details
Published in:PLoS Pathogens
Main Authors: Xiaojun Ning, David Nguyen, Laura Mentzer, Christina Adams, Hyunwook Lee, Robert Ashley, Susan Hafenstein, Jianming Hu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-09-01
Online Access:http://europepmc.org/articles/PMC3178560?pdf=render