p38α MAPK Regulates Lineage Commitment and OPG Synthesis of Bone Marrow Stromal Cells to Prevent Bone Loss under Physiological and Pathological Conditions

Bone marrow-derived mesenchymal stromal cells (BM-MSCs) are capable of differentiating into osteoblasts, chondrocytes, and adipocytes. Skewed differentiation of BM-MSCs contributes to the pathogenesis of osteoporosis. Yet how BM-MSC lineage commitment is regulated remains unclear. We show that ablat...

詳細記述

書誌詳細
出版年:Stem Cell Reports
主要な著者: Qian Cong, Hao Jia, Soma Biswas, Ping Li, Shoutao Qiu, Qi Deng, Xizhi Guo, Gang Ma, Jenny Fang Ling Chau, Yibin Wang, Zhen-Lin Zhang, Xinquan Jiang, Huijuan Liu, Baojie Li
フォーマット: 論文
言語:英語
出版事項: Elsevier 2016-04-01
オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S2213671116000345