Biomedical Advances in ABCA1 Transporter: From Bench to Bedside

ATP-binding cassette transporter A1 (ABCA1) has been identified as the molecular defect in Tangier disease. It is biochemically characterized by absence of high-density lipoprotein cholesterol (HDL-C) in the circulation, resulting in the accumulation of cholesterol in lymphoid tissues. Accumulation...

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Bibliographic Details
Published in:Biomedicines
Main Authors: Hong Y. Choi, Senna Choi, Iulia Iatan, Isabelle Ruel, Jacques Genest
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Subjects:
Online Access:https://www.mdpi.com/2227-9059/11/2/561