EBF2 Links KMT2D‐Mediated H3K4me1 to Suppress Pancreatic Cancer Progression via Upregulating KLLN

Abstract Mono‐methylation of histone H3 on Lys 4 (H3K4me1), which is catalyzed by histone‐lysine N‐methyltransferase 2D (KMT2D), serves as an important epigenetic regulator in transcriptional control. In this study, the authors identify early B‐cell factor 2 (EBF2) as a binding protein of H3K4me1. C...

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Bibliographic Details

Published in:	Advanced Science
Main Authors:	Bing Yao, Mengying Xing, Shixin Meng, Shang Li, Jingwan Zhou, Ming Zhang, Chen Yang, Shuang Qu, Yucui Jin, Hongyan Yuan, Ke Zen, Changyan Ma
Format:	Article
Language:	English
Published:	Wiley 2024-01-01
Subjects:	EBF2 H3K4me1 KLLN KMT2D pancreatic cancer
Online Access:	https://doi.org/10.1002/advs.202302037