Wg/Wnt-signaling-induced nuclear translocation of β-catenin is attenuated by a β-catenin peptide through its interference with the IFT-A complex

Summary: Wnt/Wingless (Wg) signaling is critical in development and disease, including cancer. Canonical Wnt signaling is mediated by β-catenin/Armadillo (Arm in Drosophila) transducing signals to the nucleus, with IFT-A/Kinesin 2 complexes promoting nuclear translocation of β-catenin/Arm. Here, we...

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Bibliographic Details

Published in:	Cell Reports
Main Authors:	Linh T. Vuong, Marek Mlodzik
Format:	Article
Language:	English
Published:	Elsevier 2024-06-01
Subjects:	CP: Developmental biology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124724006909