Natural reversion promotes LPS elongation in an attenuated Coxiella burnetii strain

Abstract Lipopolysaccharide (LPS) phase variation is a critical aspect of virulence in many Gram-negative bacteria. It is of particular importance to Coxiella burnetii, the biothreat pathogen that causes Q fever, as in vitro propagation of this organism leads to LPS truncation, which is associated w...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Carrie M. Long, Paul A. Beare, Diane Cockrell, Picabo Binette, Mahelat Tesfamariam, Crystal Richards, Matthew Anderson, Jessica McCormick-Ell, Megan Brose, Rebecca Anderson, Anders Omsland, Talima Pearson, Robert A. Heinzen
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-01-01
Online Access:	https://doi.org/10.1038/s41467-023-43972-y