The influence of genetic polymorphisms in drug metabolism enzymes and transporters on the pharmacokinetics of different fluvastatin formulations

The purpose of the present study was to investigate the impact of genetic polymorphism on fluvastatin pharmacokinetics. In addition, we compared the fluvastatin pharmacokinetics differences between extended-release (ER) 80 mg tablet and immediate-release (IR) 40 mg capsule in terms of drug metabolis...

Full description

Bibliographic Details

Published in:	Asian Journal of Pharmaceutical Sciences
Main Authors:	Qian Xiang, Weidang Wu, Nan Zhao, Chuan Li, Junyu Xu, Lingyue Ma, Xiaodan Zhang, Qiufen Xie, Zhuo Zhang, Jiancheng Wang, Weiren Xu, Xia Zhao, Yimin Cui
Format:	Article
Language:	English
Published:	Elsevier 2020-03-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S1818087619302922