Enhancing PQQ production in Acinetobacter calcoaceticus through uniform design and support vector regression

A novel machine learning-assisted approach for formula optimization, termed UD-SVR, is introduced by combining uniform design with support vector regression. This method was employed to optimize both the formulation and fermentation conditions for pyrroloquinoline quinone (PQQ) production by Acineto...

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التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Frontiers in Microbiology
المؤلفون الرئيسيون:	Yu-han Li, Su-hang Yao, Yan Zhou, Xiu-lan He, Zhe-ming Yuan, Qiu-long Hu, Cheng-wen Shen, Xin Li, Yuan Chen
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Frontiers Media S.A. 2025-08-01
الموضوعات:	Acinetobacter calcoaceticus PQQ uniform design support vector regression formulation optimization
الوصول للمادة أونلاين:	https://www.frontiersin.org/articles/10.3389/fmicb.2025.1556322/full