Effectiveness and safety of Guipi Mixture for the treatment of premature ventricular contractions (heart-spleen deficiency syndrome): study protocol for a randomized, double-blind, placebo-controlled, multicentre trial

IntroductionPremature ventricular contractions (PVCs) are a common arrhythmia. Long-term frequent PVCs may contribute to tachycardia-induced cardiomyopathy, exacerbate angina, or trigger more severe ventricular arrhythmias, increasing cardiovascular risk. Current Western guidelines recommend pharmac...

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Bibliographic Details

Published in:	Frontiers in Cardiovascular Medicine
Main Authors:	Yonghao Li, Yutong Wang, Ruikang Liu, Xuanchun Huang, Shiyi Tao, FuYuan Zhang, Jun Li, JingRun Cui
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2026-06-01
Subjects:	efficacy guipi mixture premature ventricular contractions protocol randomized controlled trial
Online Access:	https://www.frontiersin.org/articles/10.3389/fcvm.2026.1732874/full