Targeting metabotropic glutamate receptors for symptomatic and disease-modifying treatment in Parkinson’s disease
Abstract Degeneration of substantia nigra pars compacta dopaminergic neurons is the “hallmark” of Parkinson’s disease (PD) and is responsible for motor signs. Other neurotransmitter systems are responsible for non-motor symptoms that may precede by decades the clinical onset of motor symptoms. The p...
| Published in: | npj Parkinson's Disease |
|---|---|
| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-10-01
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| Online Access: | https://doi.org/10.1038/s41531-025-01138-1 |