In silico study of 4-phosphorylated derivatives of 1,3-oxazole as inhibitors of Candida albicans fructose-1,6-bisphosphate aldolase II

In this study, the synthesis, in vitro anti-Candida activity and molecular modeling of 4-phosphorylated derivatives of 1,3-oxazole as inhibitors of Candida albicans fructose-1,6-bisphosphate aldolase (FBA-II) are demonstrated and discussed. Significant similarity of the primary and secondary structu...

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Bibliographic Details

Published in:	Heliyon
Main Authors:	Ivan V. Semenyuta, Oleksandr L. Kobzar, Diana M. Hodyna, Volodymyr S. Brovarets, Larysa O. Metelytsia
Format:	Article
Language:	English
Published:	Elsevier 2019-04-01
Subjects:	Microbiology Pharmaceutical science Organic chemistry
Online Access:	http://www.sciencedirect.com/science/article/pii/S240584401835953X