Anti-HLA class I IgG subclasses skew platelet activation mechanisms in transfusion refractoriness

Patients requiring recurrent platelet transfusions are subject to platelet transfusion refractoriness (PTR), a therapeutic failure due to rapid clearance of transfused platelets from the circulation. One major cause of PTR is the presence in the recipient of multiple IgG directed against allogeneic...

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Bibliographic Details

Published in:	Haematologica
Main Authors:	Adèle Couvidou, Mathieu Wald, Catherine Angénieux, Juliana Pires-Marafon, Marie-Joëlle Apithy, Catherine Humbrecht, Luc-Matthieu Fornecker, Nicolas Congy-Jolivet, Arnaud Dupuis, Jérôme Rollin, Blandine Maître
Format:	Article
Language:	English
Published:	Ferrata Storti Foundation 2025-09-01
Online Access:	https://haematologica.org/article/view/12282