A Study on Pharmacokinetic Functionalities and Safety Margins of an Optimized Simvastatin Nanoformulation

A pharmaceutical formulation with favorable pharmacokinetic parameters is more likely to be efficacious and safe to overcome the failures of the drug resulting from lack of efficacy, poor bioavailability, and toxicity. In this view, we aimed to evaluate the pharmacokinetic functionalities and safety...

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Bibliographic Details
Published in:Pharmaceuticals
Main Authors: Aftab Ahmad, Unnikrishnan Meenakshi Dhanalekshmi, Kailasam Koumaravelu, Arul Prakash Francis, Shah Alam Khan, Mohammed F. Abuzinadah, Nandakumar Selvasudha
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Subjects:
nanoformulation
simvastatin
chitosan
PPAR-γ
SREBP-2.0
Online Access:https://www.mdpi.com/1424-8247/16/3/380

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https://www.mdpi.com/1424-8247/16/3/380

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