Hereditary Colon Cancer: Lynch Syndrome

Lynch syndrome is the most common familial colorectal cancer syndrome. It is linked to germline mutations in one of four DNA mismatch repair (MMR) genes. A comprehensive family history is one important way to identify at-risk individuals. The elucidation of the molecular genetics of this syndrome ha...

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Bibliographic Details
Published in:Gut and Liver
Format: Article
Language:English
Published: Gastroenterology Council for Gut and Liver 2010-06-01
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Online Access:http://gutnliver.org/journal/view.html?doi=10.5009/gnl.2010.4.2.151