Generation of two B2M knockout induced pluripotent stem cell lines (DHMi005-A-8 and DHMi005-A-9) using CRISPR/Cas9 technology

The transplantation of cells into a recipient organism has many hurdles to overcome, including the problem of T-cell-triggered cellular immune defense. Cellular rejection is based on antigen presentation by the MHC-I-complex, which is recognized by cytotoxic T lymphocytes. Elimination of the MHC-I-c...

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書誌詳細

出版年:	Stem Cell Research
主要な著者:	Katharina Abdel-Malek, Franziska von Eisenhart-Rothe, Santiago Stiegmann, Irina Gottmann, Stefanie A. Doppler, Stephanie Schneider, Heike Preisler, Harald Lahm, Martina Dreßen
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2025-09-01
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S1873506125001357