Reduced ovarian cholesterol and steroid biosynthesis along with increased inflammation are associated with high DEHP metabolite levels in human ovarian follicular fluids

The plasticizer di(2-ethylhexyl) phthalate (DEHP) is known to have endocrine-disrupting properties mediated by its many metabolites that form upon exposure in biological systems. In a previous study, we reported an inverse association between DEHP metabolites in the human ovarian follicular fluid (F...

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Bibliographic Details

Published in:	Environment International
Main Authors:	Inge Varik, Runyu Zou, Andrea Bellavia, Kristine Rosenberg, Ylva Sjunnesson, Ida Hallberg, Jan Holte, Virissa Lenters, Majorie Van Duursen, Mikael Pedersen, Terje Svingen, Roel Vermeulen, Andres Salumets, Pauliina Damdimopoulou, Agne Velthut-Meikas
Format:	Article
Language:	English
Published:	Elsevier 2024-09-01
Subjects:	DEHP Endocrine disrupting chemicals Ovary Follicular fluid Reproductive health Inflammation
Online Access:	http://www.sciencedirect.com/science/article/pii/S0160412024005464