Analysis of the characteristics and the degree of pragmatism exhibited by pragmatic-labelled trials of antineoplastic treatments

Abstract Background Pragmatic clinical trials (PCTs) are designed to reflect how an investigational treatment would be applied in clinical practice. As such, unlike their explanatory counterparts, they measure therapeutic effectiveness and are capable of generating high-quality real-world evidence....

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Bibliographic Details

Published in:	BMC Medical Research Methodology
Main Authors:	Robbe Saesen, Kevin Depreytere, Karyna Krupianskaya, Joël Langeweg, Julie Verheecke, Denis Lacombe, Isabelle Huys
Format:	Article
Language:	English
Published:	BMC 2023-06-01
Subjects:	Pragmatic trials Explanatory trials Randomized controlled trials Oncology Cancer Neoplasms
Online Access:	https://doi.org/10.1186/s12874-023-01975-9