AMPK Hyper-Activation Alters Fatty Acids Metabolism and Impairs Invasiveness of Trophoblasts in Preeclampsia

Background/Aims: Preeclampsia (PE) has long been assumed to be an ischemic disease of the placenta, although there is limited evidence as to how the ischemia impacts on the placenta. AMP-activated protein kinase (AMPK) is a key regulator of cellular energy metabolism and plays an important role in a...

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Bibliographic Details

Published in:	Cellular Physiology and Biochemistry
Main Authors:	Xiaotao Yang, Ping Xu, Fumei Zhang, Li Zhang, Yangxi Zheng, Mingyu Hu, Lulu Wang, Ting-li Han, Chuan Peng, Lianlian Wang, Li Wen, Yiwen Zeng, Rufei Gao, Yong Xia, Chao Tong, Zhu Yang, Hongbo Qi, Philip N. Baker
Format:	Article
Language:	English
Published:	Cell Physiol Biochem Press GmbH & Co KG 2018-08-01
Subjects:	Preeclampsia AMPK Placenta Fatty acids Trophoblast Metabolomics
Online Access:	https://www.karger.com/Article/FullText/492995